Transcriptional interference by RNA polymerase pausing and dislodgement of transcription factors
نویسندگان
چکیده
منابع مشابه
Transcription factors IIS and IIF enhance transcription efficiency by differentially modifying RNA polymerase pausing dynamics.
Transcription factors IIS (TFIIS) and IIF (TFIIF) are known to stimulate transcription elongation. Here, we use a single-molecule transcription elongation assay to study the effects of both factors. We find that these transcription factors enhance overall transcription elongation by reducing the lifetime of transcriptional pauses and that TFIIF also decreases the probability of pause entry. Fur...
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ژورنال
عنوان ژورنال: Transcription
سال: 2011
ISSN: 2154-1264,2154-1272
DOI: 10.4161/trns.2.1.13511